Exploring Metabolic Signatures of Ex Vivo Tumor Tissue Cultures for Prediction of Chemosensitivity in Ovarian Cancer

Predicting patient response to treatment and the onset of chemoresistance are still major challenges in oncology. Chemoresistance is deeply influenced by the complex cellular interactions occurring within the tumor microenvironment (TME), including metabolic crosstalk. We have previously shown that...

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Bibliographic Details
Main Author: Mendes, Rita (author)
Other Authors: Graça, Gonçalo (author), Silva, Fernanda (author), Guerreiro, Ana C L (author), Gomes-Alves, Patrícia (author), Serpa, Jacinta (author), Boghaert, Erwin R (author), Alves, Paula M (author), Félix, Ana (author), Brito, Catarina (author), Isidro, Inês A. (author)
Format: article
Language:eng
Published: 2022
Subjects:
biomarkers
chemoresistance
drug response
ex vivo models
metabolomics
ovarian carcinoma
tumor microenvironment
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/144474
Country:Portugal
Oai:oai:run.unl.pt:10362/144474

Internet

http://hdl.handle.net/10362/144474

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