α,α-Dialkylglycines obtained by solid phase Ugi reaction performed over isocyanide functionalized resins

The multicomponent Ugi reaction is a straightforward method that can be used for the synthesis of highly hindered C-tetrasubstituted amino acids by reacting an amine, a ketone, an acid and an isocyanide. In the present work, the synthesis of several α,α dialkylglycines (α,α-diethylglycine, Deg; α,α-...

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Bibliographic Details
Main Author: Aguiam, Nádia R. (author)
Other Authors: Castro, Vânia I. B. (author), Ribeiro, Ana I. (author), Fernandes, Rui D. V. (author), Carvalho, Carina Martins (author), Costa, Susana P. G. (author), Lima, Sílvia M. M. A. Pereira (author)
Format: article
Language:eng
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1822/34677
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/34677