Bilirubin directly disrupts membrane lipid polarity and fluidity, protein order. and redox status in rat mitochondria
Background/Aims: Unconjugated bilirubin (UCB) impairs crucial aspects of cell function and induces apoptosis in primary cultured neurones. While mechanisms of cytotoxicity begin to unfold, mitochondria appear as potential primary targets. Methods: We used
Main Author: | |
---|---|
Other Authors: | , , , |
Format: | article |
Language: | eng |
Published: |
2015
|
Subjects: | |
Online Access: | http://hdl.handle.net/10451/21053 |
Country: | Portugal |
Oai: | oai:repositorio.ul.pt:10451/21053 |