Carbon Monoxide Releasing Molecules - towards a novel antimicrobial therapeutic drug

"Carbon monoxide releasing molecules (CORMs) are carbonyl organometallic complexes that liberate controlled amounts of carbon monoxide, which is a signalling and cytoprotective molecule important in human physiology and pathophysiology. Several studies in animals have shown that CORMs are benef...

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Detalhes bibliográficos
Autor principal: Mendes, Ana Sofia Soares (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2022
Assuntos:
Texto completo:http://hdl.handle.net/10362/130065
País:Portugal
Oai:oai:run.unl.pt:10362/130065
Descrição
Resumo:"Carbon monoxide releasing molecules (CORMs) are carbonyl organometallic complexes that liberate controlled amounts of carbon monoxide, which is a signalling and cytoprotective molecule important in human physiology and pathophysiology. Several studies in animals have shown that CORMs are beneficial in the treatment of cardiovascular diseases, inflammation and organ protection. Additionally, CORMs present antimicrobial properties. (...)"