Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene

BACKGROUND Plasmodium falciparum, has developed resistance to many of the drugs in use. The recommended treatment policy is now to use drug combinations. The atovaquone-proguanil (AP) drug combination, is one of the treatment and prophylaxis options. Atovaquone (ATQ) exerts its action by inhibiting...

Full description

Bibliographic Details
Main Author: Afonso, Ana Júlia Pinto Fonseca Sieuve (author)
Other Authors: Neto, Z (author), Castro , H (author), Ferreira, Dinora (author), Alves, AC (author), Tomás , AM (author), Rosário, Virgilio Estólio do (author)
Format: article
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/10362/117175
Country:Portugal
Oai:oai:run.unl.pt:10362/117175