Development and validation of a mathematical model to predict the complexity of FMR1 allele combinations

The polymorphic trinucleotide repetitive region in the FMR1 gene 5'UTR contains AGG interspersions, particularly in normal-sized alleles (CGG < 45). In this range repetitive stretches are typically interrupted once or twice, although alleles without or with three or more AGG interspersions c...

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Detalhes bibliográficos
Autor principal: Rodrigues, Bárbara (author)
Outros Autores: Vale-Fernandes, Emídio (author), Maia, Nuno (author), Santos, Flávia (author), Marques, Isabel (author), Santos, Rosário (author), Nogueira, António J. A. (author), Jorge, Paula (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
FMR1 gene
CGG repeats
AGG interspersion pattern
Modeling allelic complexity
Allelic score
Texto completo:http://hdl.handle.net/10773/32645
País:Portugal
Oai:oai:ria.ua.pt:10773/32645

Texto Completo

http://hdl.handle.net/10773/32645

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