Molecular Dynamics Simulation of HIV Fusion Inhibitor T-1249: Insights on Peptide-Lipid Interaction

T-1249 is a peptide that inhibits the fusion of HIV envelope with the target cell membrane. Recent results indicate that T-1249, as in the case of related inhibitor peptide T-20 (enfuvirtide), interacts with membranes, more extensively in the bilayer liquid disordered phase than in the liquid ordere...

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Bibliographic Details
Main Author: Martins do Canto, António Manuel Teixeira (author)
Other Authors: Carvalho, Alfredo Jorge Palace (author), Ramalho, João Paulo Prates (author), Loura, Luís Miguel Santos (author)
Format: article
Language:por
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10174/7184
Country:Portugal
Oai:oai:dspace.uevora.pt:10174/7184