Cutting edge: IFN-γ regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection

T cell responses are important to the control of infection but are deleterious if not regulated. IFN-γ-deficient mice infected with mycobacteria exhibit enhanced accumulation of activated effector T cells and neutrophils within granulomatous lesions. These cells do not control bacterial growth and c...

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Bibliographic Details
Main Author: Cruz, Andrea (author)
Other Authors: Khader, Shabaana A. (author), Torrado, Egídio (author), Fraga, Alexandra G. (author), Pearl, John E. (author), Pedrosa, Jorge (author), Cooper, Andrea M. (author), Castro, António G. (author)
Format: article
Language:eng
Published: 2006
Subjects:
IFN-alpha
IL-17
CD4 T Cells
Mycobacterial Infection
Science & Technology
Online Access:http://hdl.handle.net/1822/5342
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/5342

Internet

http://hdl.handle.net/1822/5342

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