Human mTOR mRNA allows cap-independent translation that insures its expression and function during inhibition of global translation
The mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals from the cellular nutrient- and energy-status, acting namely on the protein synthesis machinery. Deregulation of mTOR signaling is implicated in major diseases, such as cancer, mainly due to its r...
| Main Author: | |
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| Other Authors: | , , , , , |
| Format: | conferenceObject |
| Language: | eng |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10400.18/5136 |
| Country: | Portugal |
| Oai: | oai:repositorio.insa.pt:10400.18/5136 |