Hepcidin Gene Promoter c.-1010T and c.-582G Variants are Modulators of Iron Overload Development in Individuals Carrying the H63D Mutation in the HFE Gene

Mutated HFE gene/protein is usually associated with Hereditary Hemochromatosis (HH). Despite C282Y being the most common HH-associated HFE mutation, others, such as H63D, also have an uncertain role in the pathogenesis of HH. Hepcidin is a crucial regulator of systemic iron homeostasis, controlling...

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Detalhes bibliográficos
Autor principal: Silva, Bruno (author)
Outros Autores: Pita, Lina (author), Gomes, Susana (author), Gonçalves, João (author), Faustino, Paula (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2012
Assuntos:
Hepcidin
HFE
SNPs
Iron overload
Doenças Genéticas
Texto completo:http://hdl.handle.net/10400.18/401
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/401

Texto Completo

http://hdl.handle.net/10400.18/401

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