Production of curcuminoids from tyrosine by a metabolically engineered Escherichia coli using caffeic acid as an intermediate

Curcuminoids are phenylpropanoids with high pharmaceutical potential. Herein, we report an engineered artificial pathway in Escherichia coli to produce natural curcuminoids through caffeic acid. Arabidopsis thaliana 4-coumaroyl-CoA ligase (4CL1) and Curcuma longa diketide-CoA synthase (DCS) and curc...

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Detalhes bibliográficos
Autor principal: Rodrigues, Joana Lúcia Lima Correia (author)
Outros Autores: Araújo, R. G. (author), Prather, Kristala L. J. (author), Kluskens, Leon (author), Rodrigues, L. R. (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/1822/34724
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/34724