Production of curcuminoids from tyrosine by a metabolically engineered Escherichia coli using caffeic acid as an intermediate

Curcuminoids are phenylpropanoids with high pharmaceutical potential. Herein, we report an engineered artificial pathway in Escherichia coli to produce natural curcuminoids through caffeic acid. Arabidopsis thaliana 4-coumaroyl-CoA ligase (4CL1) and Curcuma longa diketide-CoA synthase (DCS) and curc...

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Bibliographic Details
Main Author: Rodrigues, Joana Lúcia Lima Correia (author)
Other Authors: Araújo, R. G. (author), Prather, Kristala L. J. (author), Kluskens, Leon (author), Rodrigues, L. R. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/1822/34724
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/34724