Establishment of 2D Cell Cultures Derived From 3D MCF‐7 Spheroids Displaying a Doxorubicin Resistant Profile

In vitro 3D cancer spheroids generally exhibit a drug resistance profile similar to that found in solid tumors. Due to this property, these models are an appealing for anticancer compounds screening. Nevertheless, the techniques and methods aimed for drug discovery are mostly standardized for cells...

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Bibliographic Details
Main Author: Nunes, Ana S. (author)
Other Authors: Costa, Elisabete (author), Barros, Andreia S. (author), Diogo, Duarte de Melo (author), Correia, I.J. (author)
Format: article
Language:eng
Published: 2021
Subjects:
Breast Neoplasms
Cell Culture Techniques
Cell Proliferation
Cell Survival
Doxorubicin
Drug Resistance, Neoplasm
Female
Humans
MCF-7 Cells
Spheroids, Cellular
Online Access:http://hdl.handle.net/10400.6/7180
Country:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/7180

Internet

http://hdl.handle.net/10400.6/7180

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