Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication

Human immunodeficiency virus type 1 (HIV-1)-encoded Vif protein is important for viral replication and infectivity. Vif is a cytoplasmic protein that acts during virus assembly by an unknown mechanism, enhancing viral infectivity. The action of Vif in producer cells is essential for the completion o...

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Bibliographic Details
Main Author: Goncalves, J (author)
Other Authors: Silva, F (author), Freitas-Vieira, A (author), Santa-Marta, M (author), Malho, R (author), Yang, XY (author), Gabuzda, D (author), Barbas, C (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biochemistry & Molecular Biology
Online Access:http://hdl.handle.net/10451/20892
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/20892

Internet

http://hdl.handle.net/10451/20892

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