| Summary: | Background: This paper aims to identify the health-related predictors of survival in centenarians. Methods: A population-based study conducted in North Portugal (PT100) followed 140 individuals from the age of 100+ years. A detailed questionnaire at baseline was completed including information on sociodemographic characteristics, physical health, functional, cognitive, and nutritional status and life-style. Survival of study participants was checked every six months over the period of December 2013 until June 2019. Results: In the univariate Cox proportional hazards model, longer survival was associated with the absence of acute disease, better functional status, absence of physical fatigue and better cognition. Multivariate analysis revealed that acute disease, functional status and physical fatigue remained significant. Conclusions: Acute disease, functional status and physical fatigue are predictors of survival in the PT100 cen- tenarians
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