N-Cinnamoylation of Antimalarial Classics: Effects of Using Acyl Groups Other than Cinnamoyl toward Dual-Stage Antimalarials

In a follow-up study to our reports of N-cinnamoylated chloroquine and quinacrine analogues as promising dual-stage antimalarial leads with high in vitro potency against both blood-stage Plasmodium falciparum and liver-stage Plasmodium berghei, we decided to investigate the effect of replacing the c...

Full description

Bibliographic Details
Main Author: Ana Gomes (author)
Other Authors: Marta Machado (author), Lis Lobo (author), Fatima Nogueira (author), Miguel Prudencio (author), Catia Teixeira (author), Paula Gomes (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10216/82125
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82125