The role of eIF3 subunits in the mechanism of nonsense-mediated mRNA decay

Premature translation-termination codons (PTCs) or nonsense codons) can arise from mutations in germ or somatic cells. The introduction of a PTC into an mRNA can trigger nonsense-mediated decay (NMD), an important mRNA surveillance mechanism that typically recognizes and degrades mRNAs containing PT...

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Bibliographic Details
Main Author: Dias, Patrícia (author)
Other Authors: Onofre, Claudia (author), Menezes, Juliane (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2018
Subjects:
Premature Translation-termination Codons (PTCs
Nonsense Codons
mRNA Decay
Genómica Funcional e Estrutural
Doenças Genéticas
Online Access:http://hdl.handle.net/10400.18/6006
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6006

Internet

http://hdl.handle.net/10400.18/6006

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