Ugi reaction synthesis of oxindole-lactam hybrids as selective butyrylcholinesterase inhibitors

Molecular hybridization is a valuable approach in drug discovery. Combining it with multicomponent reactions is highly desirable, since structurally diverse libraries can be attained efficiently in an eco-friendly manner. In this work, isatin is used as the key building block for the Ugi 4-center 3-...

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Bibliographic Details
Main Author: Burke, Anthony (author)
Other Authors: Brandão, Predro (author), Pineiro, Marta (author), Stark, Holger (author), Lopez, Oscar (author), Fernández-Bolaños, José (author), Leitzbach, Luisa (author)
Format: article
Language:eng
Published: 2022
Subjects:
Ugi Reaction
Alzheimer's disease
Online Access:http://hdl.handle.net/10174/30930
Country:Portugal
Oai:oai:dspace.uevora.pt:10174/30930

Internet

http://hdl.handle.net/10174/30930

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