Comparison of pathway analysis and constraint-based methods for cell factory design

Computational strain optimisation methods (CSOMs) have been successfully used to exploit genome-scale metabolic models, yielding strategies useful for allowing compound overproduction in metabolic cell factories. Minimal cut sets are particularly interesting since their definition allows searching f...

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Bibliographic Details
Main Author: Vieira, Vítor (author)
Other Authors: Maia, Paulo (author), Rocha, Miguel (author), Rocha, I. (author)
Format: article
Language:eng
Published: 2019
Subjects:
Genome-scale metabolic models
Computational strain design
Metabolic pathway analysis
Evolutionary algorithms
Minimal cut sets
Growth-coupled product synthesis
Ciências Médicas::Biotecnologia Médica
Ciências Naturais::Ciências da Computação e da Informação
Science & Technology
Online Access:http://hdl.handle.net/1822/60616
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/60616

Internet

http://hdl.handle.net/1822/60616

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