Study of the cell surface proteome for the analysis of Parkinson’s disease associated DJ-1 mutations
Parkinson’s disease (PD) is a neurodegenerative disease, characterized with selective neurodegeneration and dopamine depletion. Despite most cases appear to have sporadic origin, it has been associated various monogenic mutations to the onset of a parkinsonian phenotype. DJ-1 protein is of particula...
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Format: | masterThesis |
Language: | eng |
Published: |
2018
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Online Access: | http://hdl.handle.net/10773/15483 |
Country: | Portugal |
Oai: | oai:ria.ua.pt:10773/15483 |