Study of the cell surface proteome for the analysis of Parkinson’s disease associated DJ-1 mutations

Parkinson’s disease (PD) is a neurodegenerative disease, characterized with selective neurodegeneration and dopamine depletion. Despite most cases appear to have sporadic origin, it has been associated various monogenic mutations to the onset of a parkinsonian phenotype. DJ-1 protein is of particula...

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Bibliographic Details
Main Author: Jordão, Nuno Ricardo de Oliveira (author)
Format: masterThesis
Language:eng
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10773/15483
Country:Portugal
Oai:oai:ria.ua.pt:10773/15483