Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons

Increased levels of unconjugated bilirubin, the end-product of heme catabolism, are detrimental to the central nervous system. To examine the role of apoptosis in bilirubin-induced toxicity and to characterize the biochemical pathway of cell death, we exp

Bibliographic Details
Main Author: Rodrigues, CMP (author)
Other Authors: Sola, S (author), Brites, D (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21054
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21054
Description
Summary:Increased levels of unconjugated bilirubin, the end-product of heme catabolism, are detrimental to the central nervous system. To examine the role of apoptosis in bilirubin-induced toxicity and to characterize the biochemical pathway of cell death, we exp