The first steps of adaptation of Escherichia coli to the gut are dominated by soft sweeps

The accumulation of adaptive mutations is essential for survival in novel environments. However, in clonal populations with a high mutational supply, the power of natural selection is expected to be limited. This is due to clonal interference - the competition of clones carrying different beneficial...

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Bibliographic Details
Main Author: João Barroso-Batista (author)
Other Authors: Ana Sousa (author), Marta Lourenço (author), Marie-Louise Bergman (author), Jocelyne Demengeot (author), Karina B. Xavier (author), Isabel Gordo (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10400.7/319
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/319