Structure and conformation of HIV fusion inhibitor peptide T-1249 in presence of model membranes: A molecular dynamics study

Fusion of the HIV envelope with the target cell membrane is a critical step of viral entry into the target cell. Several peptides based on the C-region of HIV gp41 protein have been used in clinical trials as possible HIV fusion inhibitors, this way controlling the progression of the infection. Some...

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Detalhes bibliográficos
Autor principal: Martins do Canto, A.M.T. (author)
Outros Autores: Palace Carvalho, A.J. (author), Prates Ramalho, J.P. (author), Loura, Luís M.S. (author)
Formato: article
Idioma:por
Publicado em: 2012
Assuntos:
Texto completo:http://hdl.handle.net/10174/5947
País:Portugal
Oai:oai:dspace.uevora.pt:10174/5947