Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado–Joseph disease (MJD) gene

Machado–Joseph disease (MJD) is a neurodegenerative disorder, caused by the expansion of the (CAG)n tract in the MJD gene. This encodes the protein ataxin-3, of unknown function. The mouse Mjd gene has a structure similar to that of its human counterpart and it also contains a TATA-less promoter. It...

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Bibliographic Details
Main Author: Costa, Maria do Carmo (author)
Other Authors: Silva, Joana Gomes da (author), Miranda, Carlos J. (author), Sequeiros, Jorge (author), Santos, Manuela M. (author), Maciel, P. (author)
Format: article
Language:eng
Published: 2004
Subjects:
Ataxin-3
Polyglutamine
Spinocerebellar ataxia
Triplet repeat
Muscle
Myocytes
MyoD
E47
Max
Arnt
Amt
Science & Technology
Online Access:https://hdl.handle.net/1822/5333
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/5333

Internet

https://hdl.handle.net/1822/5333

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