Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado–Joseph disease (MJD) gene

Machado–Joseph disease (MJD) is a neurodegenerative disorder, caused by the expansion of the (CAG)n tract in the MJD gene. This encodes the protein ataxin-3, of unknown function. The mouse Mjd gene has a structure similar to that of its human counterpart and it also contains a TATA-less promoter. It...

ver descrição completa

Detalhes bibliográficos
Autor principal: Costa, Maria do Carmo (author)
Outros Autores: Silva, Joana Gomes da (author), Miranda, Carlos J. (author), Sequeiros, Jorge (author), Santos, Manuela M. (author), Maciel, P. (author)
Formato: article
Idioma:eng
Publicado em: 2004
Assuntos:
Ataxin-3
Polyglutamine
Spinocerebellar ataxia
Triplet repeat
Muscle
Myocytes
MyoD
E47
Max
Arnt
Amt
Science & Technology
Texto completo:https://hdl.handle.net/1822/5333
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/5333

Texto Completo

https://hdl.handle.net/1822/5333

Registos relacionados