Tau deletion prevents stress-induced dendritic atrophy in prefrontal cortex: role of synaptic mitochondria

Tau protein in dendrites and synapses has been recently implicated in synaptic degeneration and neuronal malfunction. Chronic stress, awell-known inducer of neuronal/synaptic atrophy, triggers hyperphosphorylation of Tau protein and cognitive deficits. However, the cause–effect relationship between...

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Bibliographic Details
Main Author: Lopes, Sofia Oliveira (author)
Other Authors: Teplytska, Larysa (author), Silva, João Luís Vaz Lima da (author), Dioli, Chrysoula (author), Trindade, Rita (author), Morais, Mónica (author), Webhofer, Christian (author), Maccarrone, Guiseppina (author), Almeida, Osborne (author), Turck, Christoph (author), Sousa, Nuno (author), Sotiropoulos, I. (author), Filiou, Michaela (author)
Format: article
Language:eng
Published: 2017
Subjects:
Chronic stress
Dendritic atrophy
Mitochondria
Prefrontal cortex
Tau knock-out
Science & Technology
Online Access:http://hdl.handle.net/1822/46258
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/46258

Internet

http://hdl.handle.net/1822/46258

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