Mechanisms of cisplatin resistance and targeting of cancer stem cells: Adding glycosylation to the equation

Cisplatin-based chemotherapeutic regimens are the most frequently used (neo)adjuvant treatments for the majority of solid tumors. While platinum-based chemotherapeutic regimens have proven effective against highly proliferative malignant tumors, significant relapse and progression rates as well as d...

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Bibliographic Details
Main Author: Ferreira, JA (author)
Other Authors: Peixoto, A (author), Neves, M (author), Gaiteiro, C (author), Reis, CA (author), Assaraf, Y (author), Santos, L (author)
Format: article
Language:eng
Published: 2016
Subjects:
Antineoplastic Agents/pharmacology
Biomarkers, Tumor/metabolism
Cisplatin/pharmacology
Drug Resistance, Neoplasm/physiology
Glycosylation/drug effects
Humans
Neoplasms/drug therapy
Neoplasms/metabolism
Neoplasms/pathology
Neoplastic Stem Cells/drug effects
Neoplastic Stem Cells/metabolism
Online Access:https://hdl.handle.net/10216/119043
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/119043

Internet

https://hdl.handle.net/10216/119043

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