The DIS3 proteins family: role in the human transcriptome regulation and CRC tumorigenesis

The final step of eukaryotic mRNA degradation proceeds in either a 5’-3’ direction, catalyzed by XRN1, or in a 3’-5’ direction catalyzed by DIS3, DIS3L1 (the catalytic subunits of the exosome) and/or DIS3L2 (exosome-independent). Important findings over the last years have shed a new light onto the...

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Bibliographic Details
Main Author: Costa, Paulo (author)
Other Authors: Santos, Hugo (author), Gama-Carvalho, Margarida (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10400.18/5147
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/5147