Nrf2 activation by TUDCA in experimental models of Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurological disorder, mainly characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. Although the cause of PD remains elusive, several lines of evidence implicate mitochondrial dysfunction and oxidative stress as possible me...

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Detalhes bibliográficos
Autor principal: Moreira, Sara Patrícia Ferreira (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2018
Assuntos:
Nrf2 signaling pathway
DJ-1
ROS production
lipid peroxidation
MPTP/MPP+
beneficial effects of TUDCA
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Texto completo:http://hdl.handle.net/10362/31881
País:Portugal
Oai:oai:run.unl.pt:10362/31881

Texto Completo

http://hdl.handle.net/10362/31881

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