Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4

info:eu-repo/grantAgreement/FCT/5876/147258/PT We thank synchrotron radiation sources DLS (Oxford) and in particular beamline I03 (experiment number MX10121-15). We thank ARAID, MEC (CTQ2013-44367-C2-2-P, BFU2016-75633-P, CTQ2015-67727-R, CTQ2015-70524-R, and CTQ2017-85496-P), AGAUR (SGR2017-1189),...

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Bibliographic Details
Main Author: De Las Rivas, Matilde (author)
Other Authors: Paul Daniel, Earnest James (author), Coelho, Helena (author), Lira-Navarrete, Erandi (author), Raich, Lluis (author), Compañón, Ismael (author), Diniz, Ana (author), Lagartera, Laura (author), Jiménez-Barbero, Jesús (author), Clausen, Henrik (author), Rovira, Carme (author), Marcelo, Filipa (author), Corzana, Francisco (author), Gerken, Thomas A. (author), Hurtado-Guerrero, Ramon (author)
Format: article
Language:eng
Published: 2020
Subjects:
Chemistry(all)
Chemical Engineering(all)
Online Access:http://hdl.handle.net/10362/104681
Country:Portugal
Oai:oai:run.unl.pt:10362/104681
Description
Summary:info:eu-repo/grantAgreement/FCT/5876/147258/PT We thank synchrotron radiation sources DLS (Oxford) and in particular beamline I03 (experiment number MX10121-15). We thank ARAID, MEC (CTQ2013-44367-C2-2-P, BFU2016-75633-P, CTQ2015-67727-R, CTQ2015-70524-R, and CTQ2017-85496-P), AGAUR (SGR2017-1189), the National Institutes of Health (R01-GM113534, and instrument Grant GM113534-01S to T. A. Gerken), the Danish National Research Foundation (DNRF107), the FCT-Portugal [UID/Multi/04378/2013 cofinanced by the FEDER (POCI-01-0145-FEDER-007728)], and the DGA (E34_R17) for financial support. I. Comparion thanks Universidad de La Rioja for the FPI grant. F. Marcelo thanks FCT-Portugal for IF Investigator grant (IF/00780/2015) and PTNMR supported by Project 022161. E. Lira-Navarrete acknowledges her postdoctoral EMBO fellowship ALTF 1553-2015 cofunded by the European Commission (LTFCOFUND2013, GA-2013-609409) and Marie Curie Actions. H. Coelho and J. Jimenez-Barbero thank EU for the TOLLerant project. The research leading to these results has also received funding from the FP7 (2007-2013) under BioStruct-X (Grant agreement 283570 and BIOSTRUCTX 5186). We would also like to acknowledge the assistance of Juwan Lee in obtaining the GaINAc-T4 random peptide motifs.

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