Proteotoxic stress in human genome stability
Incorporation of errors during protein synthesis is denominated mistranslation. This compromises the acquisition of a correct final three dimensional structure and consequently the accumulation in the cell of proteins with abnormal conformations. Cells have protein quality control (PQC) mechanisms t...
Autor principal: | |
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Formato: | masterThesis |
Idioma: | eng |
Publicado em: |
2014
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10773/12606 |
País: | Portugal |
Oai: | oai:ria.ua.pt:10773/12606 |