Proteotoxic stress in human genome stability
Incorporation of errors during protein synthesis is denominated mistranslation. This compromises the acquisition of a correct final three dimensional structure and consequently the accumulation in the cell of proteins with abnormal conformations. Cells have protein quality control (PQC) mechanisms t...
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| Format: | masterThesis |
| Language: | eng |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/10773/12606 |
| Country: | Portugal |
| Oai: | oai:ria.ua.pt:10773/12606 |