The interplay between mRNA translation and nonsense-mediated decay in transcripts with short open reading frames

Mammalian nonsense-mediated mRNA decay (NMD) is a splicing- and translation-dependent surveillance pathway that recognizes and selectively degrades mRNAs carrying premature termination codons (PTCs). In addition, several studies have also implicated NMD in the regulation of steady-state levels of ph...

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Bibliographic Details
Main Author: Onofre, Cláudia (author)
Other Authors: Menezes, Juliane (author), Peixeiro, Isabel (author), Barbosa, Cristina (author), Romão, Luísa (author)
Format: lecture
Language:eng
Published: 2025
Subjects:
Genómica Funcional e Estrutural
Expressão Génica
Nonsense-mediated mRNA Decay
Online Access:http://hdl.handle.net/10400.18/4508
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/4508

Internet

http://hdl.handle.net/10400.18/4508

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