Analysis of genetic mutations associated with anti-malarial drug resistance in Plasmodium falciparum from the Democratic Republic of East Timor

Background: In response to chloroquine (CQ) resistance, the policy for the first-line treatment of uncomplicated malaria in the Democratic Republic of East Timor (DRET) was changed in early 2000. The combination of sulphadoxine-pyrimethamine (SP) was then introduced for the treatment of uncomplicate...

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Bibliographic Details
Main Author: Almeida, Afonso de (author)
Other Authors: Arez, Ana Paula Martins dos Reis (author), Cravo, Pedro Vitor Lemos (author), Rosário, Virgilio Estólio do (author)
Format: article
Language:eng
Published: 2021
Subjects:
in-vivo
thymidylate
genes
gene
polymerase
use
chain-reaction
malaria
point
samples
sulfadoxine-pyrimethamine
chloroquine
mutations
field
synthase
dihydrofolate-reductase
dihydropteroate-synthetase
Genetics
Parasitology
Infectious Diseases
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/117181
Country:Portugal
Oai:oai:run.unl.pt:10362/117181

Internet

http://hdl.handle.net/10362/117181

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