Retinoic acid differentially affects in vitro proliferation, differentiation and mineralization of two fish bone-derived cell lines: Different gene expression of nuclear receptors and ECM proteins

Retinoic acid (RA), the main active metabolite of vitamin A, regulates vertebrate morphogenesis through signaling pathways not yet fully understood. Such process involves the specific activation of retinoic acid and retinoid X receptors (RARs and RXRs), which are nuclear receptors of the steroid/thy...

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Bibliographic Details
Main Author: Fernández, Ignacio (author)
Other Authors: Tiago, Daniel (author), Laizé, Vincent (author), Cancela, Leonor (author), Gisbert, Enric (author)
Format: article
Language:eng
Published: 2014
Subjects:
Retinoic acid
Gene expression
Bone-derived cell lines
Chondrocyte
Osteoblast
Vitamin A
Gilthead seabream Sparus aurata
Online Access:http://hdl.handle.net/10400.1/4258
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/4258

Internet

http://hdl.handle.net/10400.1/4258

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