Transcriptomic screen for DIS3, DIS3L1 and DIS3L2-associated functional networks in colorectal cancer

The final step of cytoplasmic mRNA degradation proceeds in either a 5’-3’ direction, catalyzed by XRN1, or in a 3’-5’ direction catalyzed by the exosome and DIS3L2. In yeast, DIS3/Rrp44 protein is the catalytic subunit of the exosome. In humans, there are three known paralogues of this enzyme: DIS3,...

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Detalhes bibliográficos
Autor principal: Costa, Paulo (author)
Outros Autores: Santos, Hugo (author), Gama-Carvalho, Margarida (author), Romão, Luísa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2025
Assuntos:
Texto completo:http://hdl.handle.net/10400.18/4521
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/4521