Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes

The pyruvate uptake rate in inverted submitochondrial vesicles prepared from rat liver was optimized and further characterized; the potential inhibitory effects of the anticonvulsive drug valproic acid or 2-n-propyl-pentanoic acid (VPA), Delta(4)-valproic acid or 2-n-propyl-4-pentenoic acid and the...

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Bibliographic Details
Main Author: Aires, Catia C. P. (author)
Other Authors: Soveral, Graca (author), Luis, Paula B. M. (author), ten Brink, Herman J. (author), de Almeida, Isabel Tavares (author), Duran, Marinus (author), Wanders, Ronald J. A. (author), Silva, Margarida F. B. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21628
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21628