Monocarboxylate transporters expression is influenced by different extracellular conditions determining the effect of 3-bromopyruvate in colorectal cancer cells
Monocarboxylate transporters (MCTs) play a vital role in the glycolytic metabolism in cancer cells, exporting lactate by a proton symport mechanism, maintaining intracellular pH homeostasis and contributing for tumor microenvironment acidification and aggressiveness. 3BP is an analogous of lactate w...
Autor principal: | |
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Outros Autores: | , , , |
Formato: | conferenceObject |
Idioma: | eng |
Publicado em: |
2018
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Assuntos: | |
Texto completo: | http://hdl.handle.net/1822/73257 |
País: | Portugal |
Oai: | oai:repositorium.sdum.uminho.pt:1822/73257 |