Monocarboxylate transporters expression is influenced by different extracellular conditions determining the effect of 3-bromopyruvate in colorectal cancer cells
Monocarboxylate transporters (MCTs) play a vital role in the glycolytic metabolism in cancer cells, exporting lactate by a proton symport mechanism, maintaining intracellular pH homeostasis and contributing for tumor microenvironment acidification and aggressiveness. 3BP is an analogous of lactate w...
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| Other Authors: | , , , |
| Format: | conferenceObject |
| Language: | eng |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://hdl.handle.net/1822/73257 |
| Country: | Portugal |
| Oai: | oai:repositorium.sdum.uminho.pt:1822/73257 |