p53 dephosphorylation and p21(Cip1/Waf1) translocation correlate with caspase-3 activation in TGF-beta 1-induced apoptosis of HuH-7 cells

The p53 tumor suppressor gene product plays an important role in the regulation of apoptosis. Transforming growth factor beta1 (TGF-beta1)-induced apoptosis in hepatic cells is associated with reduced expression of the retinoblastoma protein (pRb) and sub

Bibliographic Details
Main Author: Fan, G (author)
Other Authors: Ma, X (author), Wong, PY (author), Rodrigues, CMP (author), Steer, CJ (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biochemistry & Molecular Biology
Cell Biology
Online Access:http://hdl.handle.net/10451/21066
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21066

Internet

http://hdl.handle.net/10451/21066

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