The role of efflux pumps in Schistosoma mansoni Praziquantel resistant phenotype

Background: Schistosomiasis is a neglected disease caused by a trematode of the genus Schistosoma that is second only to malaria in public health significance in Africa, South America, and Asia. Praziquantel (PZQ) is the drug of choice to treat this disease due to its high cure rates and no signific...

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Bibliographic Details
Main Author: Pinto-Almeida, António (author)
Other Authors: Mendes, Tiago (author), Armada, Ana (author), Belo, Silvana (author), Carrilho, Emanuel (author), Viveiros, Miguel (author), Afonso, Ana (author)
Format: article
Language:eng
Published: 2018
Subjects:
Online Access:https://doi.org/10.1371/journal.pone.0140147
Country:Portugal
Oai:oai:run.unl.pt:10362/36593