Trousseau’s syndrome due to asymptomatic pancreatic adenocarcinoma

The authors report a case of Trousseau’s syndrome presenting in a previously asymptomatic 58-year-old man diagnosed with pancreatic adenocarcinoma and liver metástases during a workup prompted by migratory venous thrombosis and pulmonary embolism. It was followed by an ischaemic stroke that occurred...

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Bibliographic Details
Main Author: Murinello,António (author)
Other Authors: Guedes,Pedro (author), Rocha,Gizela (author), Serrano,Ana (author), Figueiredo,António (author), Damásio,Helena (author), Freire,João (author), Cunha,Fernando (author), Alves,Liliana (author)
Format: report
Language:eng
Published: 2013
Subjects:
Trousseau’s syndrome
Migratory thrombophlebitis
Heparin
Occult malignancy
Pancreatic adenocarcinoma
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-81782013000400007
Country:Portugal
Oai:oai:scielo:S0872-81782013000400007
Description
Summary:The authors report a case of Trousseau’s syndrome presenting in a previously asymptomatic 58-year-old man diagnosed with pancreatic adenocarcinoma and liver metástases during a workup prompted by migratory venous thrombosis and pulmonary embolism. It was followed by an ischaemic stroke that occurred while the patient was just one day off anticoagulante therapy with low-molecular-weight heparin to allow for liver and pancreatic biopsies. Trousseau’s syndrome is defined by recurrent or migratory venous thrombosis, arterial embolism caused by non-bacterial thrombotic endocarditis, or both, in patients with underlying malignancy. Treatment relies on the lifelong administration of heparin, and its interruption - however brief - may promote new thrombotic events.

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