Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3

Global cerebral ischemia induces selective acute neuronal injury of the CA1 region of the hippocampus. The type of cell death that ensues may include different programmed cell death mechanisms namely apoptosis and necroptosis, a recently described type of programmed necrosis. We investigated whether...

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Bibliographic Details
Main Author: Vieira, M. (author)
Other Authors: Fernandes, J. (author), Carreto, L. (author), Anuncibay-Soto, B. (author), Santos, M. (author), Han, J. (author), Fernández-López, A. (author), Duarte, C. B. (author), Carvalho, A. L. (author), Santos, A. E. (author)
Format: article
Language:eng
Published: 1000
Subjects:
Cerebral ischemia
Necroptosis
Necrostatin-1
Oxygen-glucose deprivation
Receptor-interacting Protein Kinase 3
Online Access:http://hdl.handle.net/10773/23292
Country:Portugal
Oai:oai:ria.ua.pt:10773/23292

Internet

http://hdl.handle.net/10773/23292

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