Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters

Gene expression depends on binding of transcriptional regulators to gene promoters, a process controlled by signalling pathways. The transcriptional repressor BCL-6downregulates genes involved in cell cycle progression and becomes inactivated following phosphorylation by the Rac1 GTPase activated pr...

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Bibliographic Details
Main Author: Barros, Patricia (author)
Other Authors: Lam, Eric (author), Jordan, Peter (author), Matos, Paulo (author)
Format: conferenceObject
Language:eng
Published: 2012
Subjects:
Vias de Transdução de Sinal e Patologias Associadas
Rac1
Gene Transcription
Colorectal Cancer
Online Access:http://hdl.handle.net/10400.18/1027
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/1027

Internet

http://hdl.handle.net/10400.18/1027

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