Multi-criterion approaches for the in silico optimization of mutant microorganisms

create mutants for the production of valuable compounds is, in Metabolic Engineering, a promising, while complex task. Approaches to tackle this problem have been proposed and included MILP-based techniques (OptKnock [1]), that lacked the possibility of including non-linear objective functions. More...

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Detalhes bibliográficos
Autor principal: Maia, Paulo (author)
Outros Autores: Ferreira, Eugénio C. (author), Rocha, Miguel (author), Rocha, I. (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2009
Texto completo:https://hdl.handle.net/1822/9517
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/9517