Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical,...

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Detalhes bibliográficos
Autor principal: Figueiredo, Andrea G. P. R. (author)
Outros Autores: Figueiredo, Ana R. P. (author), Alonso-Varona, Ana (author), Fernandes, Susana C. M. (author), Palomares, Teodoro (author), Rubio-Azpeitia, Eva (author), Barros-Timmons, Ana (author), Silvestre, Armando J. D. (author), Neto, Carlos Pascoal (author), Freire, Carmen S. R. (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
CELLULOSE
HYDROGELS
COMPOSITES
SCAFFOLDS
DIFFUSION
DELIVERY
PHEMA
Texto completo:http://hdl.handle.net/10773/19769
País:Portugal
Oai:oai:ria.ua.pt:10773/19769
Descrição
Resumo:A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.

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