Genetic characterisation of the ethambutol resistance-determining region in Mycobacterium tuberculosis

Ethambutol (EMB) is a first-line antitubercular drug that inhibits arabinogalactan and lipoarabinomannan biosynthesis. Resistance to EMB has traditionally been associated with embB mutations, especially in the Met306 codon. In this study, the region encom. - Fundacao Calouste Gulbenkian, Lisbon, Por...

Full description

Bibliographic Details
Main Author: Perdigao, Joao (author)
Other Authors: Macedo, Rita (author), Ribeiro, Ana (author), Brum, Laura (author), Portugal, Isabel (author)
Format: article
Language:eng
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10451/21542
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21542