Comparison of Fluorescence, 31P NMR, and 7Li NMR Spectroscopic Methods for Investigating Li+/Mg2+ Competition for Biomolecules

The biochemical action of lithium in the treatment of manic-depressive illness is still unknown. One hypothesis is that Li+ competes for Mg2+-binding sites in biomolecules. We report here our studies on metal ion competition by three distinct methods: fluorescence, 31P NMR, and 7Li NMR spectroscopy,...

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Bibliographic Details
Main Author: Amari, Louis (author)
Other Authors: Layden, Brian (author), Rong, Qinfen (author), Geraldes, Carlos F. G. C. (author), Freitas, Duarte Mota de (author)
Format: article
Language:eng
Published: 1999
Subjects:
Online Access:http://hdl.handle.net/10316/3898
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/3898