Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens

There is accumulating evidence that the nucleus accumbens (NAc) has an important role in the pathophysiology of depression. As the NAc is a key component in the neural circuitry of reward, it has been hypothesized that anhedonia, a core symptom of depression, might be related to dysfunction of this...

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Bibliographic Details
Main Author: João, Bessa (author)
Other Authors: Morais, Mónica (author), Marques, Fernanda (author), Pinto, Luísa (author), Palha, Joana Almeida (author), Sousa, Nuno (author)
Format: article
Language:eng
Published: 2013
Subjects:
anhedonia
antidepressants
depression
neuroplasticity
remodeling
stress
Science & Technology
Online Access:http://hdl.handle.net/1822/25086
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/25086

Internet

http://hdl.handle.net/1822/25086

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