Expansion of activated cxcr5+icos+ tfh cells and plasmablasts induced by seasonal influenza vaccine is impaired in anti-il-6r treated rheumatoid arthritis patients

Objectives: To investigate the importance of IL-6 for the in vivo differentiation of human Tfh cells, taking advantage of influenza vaccination in patients under anti-IL-6R therapy.

Detalhes bibliográficos
Autor principal: Romao, V.C. (author)
Outros Autores: Agua-Doce, A. (author), Polido-Pereira, J. (author), Barros, R. (author), Lopes, I.P. (author), Seixas, M.I. (author), Saavedra, M.J. (author), Sacadura-Leite, E. (author), Rebelo-de-Andrade, H. (author), Fonseca, J.E. (author), Graca, L. (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2019
Assuntos:
Influenza
Influenza Vaccination
Influenza Vaccine
Infecções Respiratórias
Texto completo:http://hdl.handle.net/10400.18/6354
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6354
Descrição
Resumo:Objectives: To investigate the importance of IL-6 for the in vivo differentiation of human Tfh cells, taking advantage of influenza vaccination in patients under anti-IL-6R therapy.

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